Component-resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan-allergens
Título de la tesis:
Component-resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan-allergens
Autor/es:
Barber, D. - Torre, F. de la - Lombardero, M. - Antepara, I. - Colas, C. - Davila, I. - Tabar, I.A. - Vidal, C. - Villalba, M. - Salcedo Duran, Gabriel - Rodriguez, R.
Tipo de documento:
Artículo
Universidad:
E.T.S.I. Agrónomos (UPM)
Departamento:
Biotecnologia
Idioma:
Palabras clave:
Fecha de la defensa:
Noviembre 2009-01-01
Notas:
Resumen: BACKGROUND Allergy diagnosis needs to be improved in patients suffering from pollen polysensitization due to the existence of possible confounding factors in this type of patients. OBJECTIVE To evaluate new diagnostic strategies by comparing skin responses to pan-allergens and conventional allergenic extracts with specific IgE (sIgE) to purified allergen molecules. METHODS One thousand three hundred and twenty-nine pollen-allergic patients were diagnosed by a combination of an in vitro method with a panel of 13 purified allergens, including major allergens and pan-allergens, using a high-capac...
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